Cytotoxic effect of anti-H-2 and anti-Ia antisera on human B and T cells

Autor:	G.Gy. Petranyi, G. Györffy, P. Iványi, E. Ivašková, H. Pavljukoyá, E. Gyódi
Rok vydání:	1977
Předmět:	Antiserum B-Lymphocytes Isoantigens Immune Sera T-Lymphocytes Immunology General Medicine Biology Cytotoxicity Tests Immunologic Molecular biology Peripheral blood Titer Epitopes Mice Antigen Cytotoxic T cell Animals Humans Cytotoxicity
Zdroj:	Scandinavian journal of immunology. 6(5)
ISSN:	0300-9475
Popis:	Anti-H-2 and anti-Ia alloimmune mouse antisera were tested by the microcytotoxicity test on human peripheral blood B- and T-cell preparations. Anti-H-2 antisera react by a higher titer and/or cytotoxicity scoring grade on B cells than on T cells. Anti-Ia antisera react practically only with B cells. It was assumed that anti-H-2 antisera contain two components. One component reacts specifically with certain HLA-A-or -B-locus antigens or other closely linked gene products. The other component reacts predominantly or only with B-cell determinants; the specificity of the latter component has not yet been studied in sufficient detail.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0693d12e59a68f13059097047d1c5e6a https://pubmed.ncbi.nlm.nih.gov/70061 Zobrazit plný text záznamu Plný text