TRTools: a toolkit for genome-wide analysis of tandem repeats
| Autor: | Mousavi, Nima, Margoliash, Jonathan, Pusarla, Neha, Saini, Shubham, Yanicky, Richard, Gymrek, Melissa |
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| Přispěvatelé: | Schwartz, Russell |
| Rok vydání: | 2020 |
| Předmět: |
Statistics and Probability
Genotype Bioinformatics Computer science Genome wide analysis Documentation Computational biology computer.software_genre Biochemistry Mathematical Sciences 03 medical and health sciences 0302 clinical medicine Tandem repeat Information and Computing Sciences Genetics Molecular Biology Genotyping Gene Library 030304 developmental biology 0303 health sciences Database Human Genome 030302 biochemistry & molecular biology Biological Sciences Applications Notes Computer Science Applications Computational Mathematics ComputingMethodologies_PATTERNRECOGNITION Computational Theory and Mathematics Tandem Repeat Sequences computer Software 030217 neurology & neurosurgery |
| Zdroj: | Bioinformatics Bioinformatics (Oxford, England), vol 37, iss 5 |
| Popis: | Summary A rich set of tools have recently been developed for performing genome-wide genotyping of tandem repeats (TRs). However, standardized tools for downstream analysis of these results are lacking. To facilitate TR analysis applications, we present TRTools, a Python library and suite of command line tools for filtering, merging and quality control of TR genotype files. TRTools utilizes an internal harmonization module, making it compatible with outputs from a wide range of TR genotypers. Availability and implementation TRTools is freely available at https://github.com/gymreklab/TRTools. Detailed documentation is available at https://trtools.readthedocs.io. Supplementary information Supplementary data are available at Bioinformatics online. |
| Databáze: | OpenAIRE |
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