Source of Ovarian Preovulatory Progesterone
| Autor: | G. C. Blaha, W. W. Leavitt, C. G. Bosley |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Ovulation
endocrine system medicine.medical_specialty Chromatography Gas media_common.quotation_subject Hamster Ovary General Biochemistry Genetics and Molecular Biology Estrus Corpus Luteum Pregnancy Cricetinae Internal medicine medicine Animals Endocrine system Progesterone media_common Estrous cycle urogenital system Chemistry Theca interna General Medicine medicine.anatomical_structure Endocrinology Female Corpus luteum hormones hormone substitutes and hormone antagonists Golden hamster |
| Zdroj: | Nature New Biology. 234:283-284 |
| ISSN: | 2058-1092 0090-0028 |
| DOI: | 10.1038/newbio234283a0 |
| Popis: | AN increase in plasma progesterone has been detected before ovulation in several species. There is, however, no definitive information as to which ovarian compartments produce this progesterone. Previous results with the golden hamster have demonstrated a preovulatory progesterone surge after the critical period for gonadotrophin release on the afternoon of pro-oestrus (day 4)1,2. This is paralleled by the development of 3β-hydroxysteroid dehydrogenase (3βHSD) activity in the theca interna and granulosa of pre-ovulatory follicles3, suggesting they could be a source of preovulatory progesterone. As the interstitium also contains 3βHSD activity, it could be an additional source of progesterone3. Hamster corpora lutea, however, have negligible 3βHSD activity during pro-oestrus3 and are not capable of producing progesterone when isolated and incubated in vitro (Leavitt et al., unpublished work). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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