In situfluoride retention and remineralization of incipient carious lesions after the application of different concentrations of fluoride
| Autor: | Elmar Hellwig, Markus Jörg Altenburger, Jörg F. Schirrmeister, Manfred Klasser, Adrian Lussi |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male In situ Inorganic chemistry Amine fluoride Dental Caries Tooth Artificial Young Adult chemistry.chemical_compound Animal science Double-Blind Method Animals Humans Fluorides Topical Dental Enamel General Dentistry Remineralisation Cross-Over Studies Dose-Response Relationship Drug Enamel paint Chemistry Initial caries Middle Aged Cariostatic Agents Linear relationship Tooth Remineralization visual_art visual_art.visual_art_medium Cattle Female Fluoride In situ study |
| Zdroj: | European Journal of Oral Sciences. 117:58-63 |
| ISSN: | 1600-0722 0909-8836 |
| DOI: | 10.1111/j.1600-0722.2008.00585.x |
| Popis: | Limited information is available on the time-dependent or dosage-dependent cariostatic efficacy of highly concentrated fluoride compounds. This good clinical practice-conforming, double-blind, placebo-controlled, crossover in situ study tested the hypothesis that a 1.0% amine fluoride fluid is superior to a 0.5% amine fluoride fluid regarding fluoride retention and mineral change in initial caries enamel lesions over a period of 28 d. Fluoride retention was significantly higher after application of the two fluoride fluids compared with placebo but had decreased in both groups to similar levels after only 1 wk. Mineral gain was significantly higher for both verum groups compared with placebo. The use of 1% fluoride fluid resulted in significantly higher remineralization compared with the use of 0.5% fluoride fluid. For both fluoride fluids mineral gain followed a linear relationship with time during the experimental period, indicating a possible further uptake of mineral, even after 4 wk. |
| Databáze: | OpenAIRE |
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