Guillain-Barré Syndrome Heralding the Diagnosis of Hodgkin Lymphoma: A Case Report
| Autor: | Saleh Alkhonezan, Sara Abdullah Al Najjar, Alawi Aqel Al-Attas, Abdulrahman Yousef Aldayel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Lymphoma Malignancy lcsh:RC346-429 immune system diseases hemic and lymphatic diseases Biopsy medicine lcsh:Neurology. Diseases of the nervous system hodgkin’s lymphoma medicine.diagnostic_test Guillain-Barre syndrome biology Hodgkin's lymphoma business.industry medicine.disease Guillain-Barré syndrome Neuropathy Lymphatic system biology.protein Neurology (clinical) Differential diagnosis Antibody business Single Case − General Neurology |
| Zdroj: | Case Reports in Neurology Case Reports in Neurology, Vol 12, Iss 3, Pp 365-372 (2020) |
| ISSN: | 1662-680X |
| Popis: | Lymphoma is a prevalent type of lymphoid tissue malignancy that is seldom associated with Guillain-Barré syndrome (GBS). In the majority of instances, both Hodgkin’s and non-Hodgkin’s lymphoma are not proceeded by GBS. Here, we report on a case of a young patient with a manifestation and investigation suggestive of GBS, signaling an unconfirmed diagnosis of Hodgkin’s lymphoma. A cerebrospinal fluid test revealed an albuminocytological dissociation with a noteworthy rise in protein (2.32 g/L). The patient was initiated on intravenous immunoglobulin (IVIG) treatment and then showed dramatic improvement after the third dose of IVIG. His constitutional presentation alongside high inflammatory labs prompted further investigation. An enhanced pan-computed tomography scan showed multiple enlarged mediastinal and hilar lymph nodes that were confirmed as Hodgkin’s lymphoma after biopsy. Brentuximab was initiated immediately after IVIG therapy. This case highlights consideration of Hodgkin’s lymphoma as a differential diagnosis under the auspices of GBS. |
| Databáze: | OpenAIRE |
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