Potassium-induced conversion of ventricular fibrillation after aortic declamping
| Autor: | Per Steinar Halvorsen, Sven M. Almdahl, Magne Eide, Jens Damstuen, Per Mølstad, Terje Veel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Male
Blood transfusion medicine.medical_treatment Potassium Sodium Chloride Left ventricular hypertrophy law.invention Potassium Chloride Calcium Chloride law Risk Factors Magnesium Registries Infusions Intravenous Aorta Aged 80 and over Cardiopulmonary Bypass Cardiac Pacing Artificial Middle Aged Constriction Treatment Outcome Anesthesia Ventricular Fibrillation Cardiology Heart Arrest Induced Female Cardiology and Cardiovascular Medicine Perfusion Anti-Arrhythmia Agents Pulmonary and Respiratory Medicine Adult medicine.medical_specialty Electric Countershock chemistry.chemical_element Risk Assessment medicine.artery Internal medicine medicine Cardiopulmonary bypass Humans Cardiac Surgical Procedures Aged Chi-Square Distribution business.industry Original Articles medicine.disease Bicarbonates Logistic Models chemistry Ventricular fibrillation Multivariate Analysis Surgery business |
| Popis: | OBJECTIVES: The anti-fibrillatory effect of potassium is well recognized from experimental models. There have, however, been very few clinical reports on the use of potassium to convert ventricular fibrillation (VF) after cardioplegic arrest. METHODS: In total, 8465 adult patients undergoing cardiac operations on cardiopulmonary bypass (CPB) and with cold antegrade crystalloid cardioplegic arrest were consecutively enrolled in a database. Patients with VF after removal of the aortic clamp were given 20 mmol potassium, and if needed an extra 10 mmol, in the perfusion line and the conversion rate was registered. Preoperative and intraoperative factors possibly related to the occurrence of post-ischaemic VF were assessed. RESULTS: Of these, 1721 (20%) patients had VF and 1366 of these (79%) were successfully treated with potassium infusion. Only 355 (21%) patients (4% of all operations) had direct-current countershock. The need for pacing was lower in the treatment group compared with the non-treatment group (P |
| Databáze: | OpenAIRE |
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