Function of the Male Sex Organs in Heroin and Methadone Users
| Autor: | Eli Robins, Kenneth L. Polakoski, Theodore J. Cicero, Roy D. Bell, James H. Allison, Walter G. Wiest |
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| Rok vydání: | 1975 |
| Předmět: |
Adult
Male medicine.medical_specialty Methadone maintenance Cell Count Genitalia Male Heroin Erectile Dysfunction Cell Movement Internal medicine mental disorders medicine Humans Ejaculation Testosterone Sex organ Orgasm Sperm motility Heroin Dependence business.industry Prostate Seminal Vesicles General Medicine Control subjects Spermatozoa Sperm Endocrinology business Methadone medicine.drug |
| Zdroj: | New England Journal of Medicine. 292:882-887 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm197504242921703 |
| Popis: | The function of the secondary sex organs was found to be markedly impaired in 29 participants in a methadone maintenance program. The ejaculate volume and seminal vesicular and prostatic secretions were reduced by over 50 per cent in methadone clients, as compared to 16 heroin addicts and 43 narcotic-free controls. Serum testosterone levels were also approximately 43 per cent lower in methadone clients than in controls or heroin users. Although the sperm count of methadone clients was more than twice the control levels, reflecting a lack of sperm dilution by secondary-sex-organ secretions, the sperm motility of these subjects was markedly lower than normal. On all measures of secondary-sex-organ and testicular function, heroin addicts appeared to fall between the methadone and control subjects, but, with the exception of sperm motility, the deviation from control values did not reach statisitcal significance. |
| Databáze: | OpenAIRE |
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