Living Cell Nanoporation and Exosomal RNA Analysis Platform for Real-Time Assessment of Cellular Therapies

Autor:	Yan Sheng, Zena Huang, Tenghua Zhang, Feiyang Qian, Yuqing Zhu, Zaizai Dong, Qingyang Zhang, Qi Lei, Fanhui Kong, Yuqiong Wang, Maddie Walden, Stefan Wuttke, Lingqian Chang, Wei Zhu, Jiaming Hu
Rok vydání:	2022
Předmět:	MicroRNAs Colloid and Surface Chemistry General Chemistry Exosomes Transfection Biochemistry Catalysis
Zdroj:	Journal of the American Chemical Society. 144:9443-9450
ISSN:	1520-5126 0002-7863
DOI:	10.1021/jacs.2c02268
Popis:	Efficient transfection of therapeutic agents and timely potency testing are two key factors hindering the development of cellular therapy. Here we present a cellular-nanoporation and exosome assessment device, a quantitative platform for nanochannel-based cell electroporation and exosome-based
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0684285a72d2693a9e460344a674f05e https://doi.org/10.1021/jacs.2c02268 Zobrazit plný text záznamu