Permeability of the normal rat brain, spinal cord and dorsal root ganglia microcirculations to immunoglobulins G
| Autor: | Georges Azzi, B. Bellon, Claude Bouchaud, Jocelyne Fleury-Feith, Jean-François Bernaudin |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Central nervous system
Blood–brain barrier Pineal Gland law.invention Capillary Permeability Pineal gland law Ganglia Spinal Parenchyma medicine Animals Horseradish Peroxidase Cerebral Cortex biology Brain Cell Biology General Medicine Anatomy Spinal cord Rats medicine.anatomical_structure Spinal Cord Blood-Brain Barrier Rats Inbred Lew Cerebral cortex Immunoglobulin G biology.protein Antibody Electron microscope |
| Zdroj: | Biology of the Cell. 68:31-36 |
| ISSN: | 0248-4900 |
| Popis: | The distribution of blood-borne immunoglobulins G (IgG) was studied in the cerebral cortex, pineal gland, spinal cord and dorsal root ganglia of normal Lewis rats using the detection of autologous anti-horseradish peroxidase (HRP) antibodies. This detection was performed by means of light and electron microscopy. This study demonstrated that, in the cerebral cortex and the spinal cord microcirculations, endothelial cells are a restrictive barrier against IgG while IgG are able to diffuse into the perivascular parenchyma of the pineal gland and spinal ganglia. |
| Databáze: | OpenAIRE |
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