Adenocarcinoma of the appendix with extra-appendicular spread: Clinico-surgical and histologic analysis of 27 cases

Autor: Francisco José Morera Ocón, Elena Muñoz Forner, Samuel Navarro Fos, Clara Navarro Campoy, Javier Gallego Plazas, Bruno Camps Vilata
Rok vydání: 2017
Předmět:
Adult
Male
Oncology
medicine.medical_specialty
030230 surgery
03 medical and health sciences
Peritoneal Neoplasm
Adenocarcinoma mucinoso
Appendicular neoplasia
Carcinomatosis peritoneal
Hyperthermic intraperitoneal chemotherapy
Mucinous adenocarcinoma
Neoplasia apendicular
Peritoneal carcinomatosis
Pseudomixoma peritoneal
Pseudomixoma peritonei
Quimioterapia intraperitoneal hipertérmica
0302 clinical medicine
Internal medicine
Ascites
medicine
Humans
Pseudomyxoma peritonei
Neoplasm Invasiveness
Peritoneal Neoplasms
Aged
Retrospective Studies
business.industry
Retrospective cohort study
Middle Aged
Prognosis
Pseudomyxoma Peritonei
medicine.disease
Adenocarcinoma
Mucinous
Appendix
medicine.anatomical_structure
Appendiceal Neoplasms
030220 oncology & carcinogenesis
Adenocarcinoma
Female
Hyperthermic intraperitoneal chemotherapy
Radiology
medicine.symptom
business
Ovarian cancer
Follow-Up Studies
Zdroj: MEDICINA CLINICA
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-FISABIO. Repositorio Institucional de Producción Científica
ISSN: 0025-7753
1578-8989
Popis: Background and objectives Appendiceal neoplasms with extra-appendiceal spread may show different clinical patterns with pseudomyxoma peritonei (PMP) being one of them. We analyse the results in a series of patients treated in our centre. Material and methods Retrospective study of patients operated on for appendiceal peritoneal carcinomatosis from January 2012 to May 2015. Results Twenty-seven consecutive patients were included. Median age 63 years (26–73); 14 were men. Peritoneal carcinomatosis index = 16 ± 8 (3–31). The suspected preoperative origins were appendix in 23, ovary in 3 and urothelial in one. Postoperative mortality in 2 patients (7.4%). The remaining 36% presented morbidity. Major morbidity (Clavien-Dindo grades 3 and 4) occurred in 3 patients (12%). Conclusions Mucinous adenocarcinomas with extra-appendiceal spread may present as PMP with mucinous ascites, jelly-nodular carcinomatosis without ascites, nodular or desmoplasic plates carcinomatosis without jelly mass/nodules. Histology is not correlated to clinical picture. Preoperative diagnosis of mucinous ovarian cancer in peritoneal carcinomatosis scenario may increase the doubt of their ovarian origin and force an appendiceal origin to be ruled out.
Databáze: OpenAIRE
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