Supplementary Figure 2 from Neoadjuvant Enzalutamide Prior to Prostatectomy
Autor: | Mary-Ellen Taplin, Alison Hannah, Andrew Krivoshik, Gabriel P. Haas, Adam Kibel, Rosina T. Lis, Alvin M. Matsumoto, Peter S. Nelson, Steven P. Balk, Stephen Plymate, Brett T. Marck, Philip W. Kantoff, Kenneth Wu, William Novotny, Martin Sanda, Daniel W. Lin, Kim N. Chi, Elahe A. Mostaghel, Glenn J. Bubley, Neil Fleshner, Martin E. Gleave, Anthony M. Joshua, Maria S. Tretiakova, Bruce Montgomery |
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Rok vydání: | 2023 |
DOI: | 10.1158/1078-0432.22463937 |
Popis: | Prostate androgen levels after enza or enza/dut/LHRHa. Tissue androgens from prostatectomy specimens after 6 months of therapy were measured by mass spectroscopy to determine levels of (A) pregnenolone, (B) progesterone, (C) DHEA, (D) AED, (E) testosterone, and (F) DHT. P values were calculated using the nonparametric Mann-Whitney test. Limits of quantification were 0.015 pg/mg for AED, progesterone, and testosterone, 0.03 pg/mg for DHT and pregnenolone, and 0.49 pg/mg for DHEA. |
Databáze: | OpenAIRE |
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