0273 : Functional tricuspid regurgitation and renal function and there prognosis value in patients with heart failure: Moroccan experience

Autor: Fatima Arhlade, Rachida Habbal, Fatimazahra Sabri, Mariam Abelhad
Rok vydání: 2016
Předmět:
Zdroj: Archives of Cardiovascular Diseases Supplements. 8:238
ISSN: 1878-6480
DOI: 10.1016/s1878-6480(16)30452-9
Popis: Purpose Many recent studies suggests the important role for systemic venous congestion and functional tricuspid regurgitation (FTR) in the pathophysiology of renal dysfunction which is common in heart failure. We thought to investigate the role of FTR as a determinant of renal dysfunction and a predictor of poor prognosis in chronic systolic heart failure Moroccan patients. Methods and results Over 1422 patients only 132 how had moderate or severe FTR were enrolled (mean age 64 ± 5 years) with chronic heart failure and left ventricular ejection fraction less than 45%. The period of study was 6 years. The FTR severity was quantified by transthoracic echocardiography. Renal function was evaluated with the estimated glomerular filtration rate measured by the simplified Modification of Diet in Renal Disease formula (MDRD). The association between moderate/severe FTR and renal dysfunction, and its impact on heart failure episodes (acute heart failure decompensation) were also assessed. The interaction between moderate/severe FTR with tricuspid annular plane systolic excursion less than 16?mm was found to be an independent determinant of renal dysfunction [40,8%]. Moderate/severe FTR and tricuspid annular plane systolic excursion below 16?mm were related to the heart failure episodes (20%). Moreover, we find that worse outcome (acute heart failure decompensation and readmissions) was associated with moderate/severe FTR. Conclusion Our data is consistent with the literature and prove that even in our population, the combination of significant FTR and right ventricular dysfunction, is independently associated with renal dysfunction. The presence of significant FTR is related to an excess event rate of heart failure and has significant impact on outcome. The author hereby declares no conflict of interest
Databáze: OpenAIRE
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