Treatment and prevention of atrial fibrillation with nonantiarrhythmic pharmacologic therapy

Autor: Todd Florin, Gervasio A. Lamas, Cesar A. Conde, Hector Lozano
Rok vydání: 2005
Předmět:
Zdroj: Heart Rhythm. 2:1000-1007
ISSN: 1547-5271
DOI: 10.1016/j.hrthm.2005.05.020
Popis: Atrial fibrillation is one of the most frequent heart rhythm disturbances found in clinical practice. Anticoagulation, rate control, cardioversion, and ablative procedures have been the mainstay of treatment. The frequent recurrence of atrial fibrillation and the side effects when antiarrhythmic drugs are used have led to dissatisfaction with available treatment of this arrhythmia. Pharmacologic therapy with angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, statins, and perhaps aldosterone and calcium channel blockers may have a role in the prevention of atrial fibrillation onset and recurrence. We summarize the possible biologic mechanisms and the clinical observations supporting the use of non-antiarrhythmic medications in the prevention of atrial fibrillation.
Databáze: OpenAIRE