Transfusion requirements after HLA-identical marrow transplantation in 82 patients with aplastic anemia
| Autor: | Sherrill J. Slichter, Jean E. Sanders, Thomas Ed, Wulff Jc, Banaji M, P Stewart, Reginald A. Clift, Buckner Cd, Rainer Storb, Santner Tj |
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| Rok vydání: | 1983 |
| Předmět: |
Human leukocyte antigen
Platelet Transfusion ABO Blood-Group System HLA Antigens ABO blood group system medicine Humans Platelet Blood Transfusion Aplastic anemia Bone Marrow Transplantation Marrow transplantation business.industry Anemia Aplastic hemic and immune systems Hematology General Medicine medicine.disease Red blood cell medicine.anatomical_structure Bone transplantation Immunology Multivariate statistical business Erythrocyte Transfusion circulatory and respiratory physiology |
| Zdroj: | Vox sanguinis. 44(6) |
| ISSN: | 0042-9007 |
| Popis: | Red blood cell (RBC) and platelet (PLT) transfusion requirements during the first 13 weeks after HLA-identical marrow transplantation were studied in 82 patients with aplastic anemia. On the average, patients were given 9 units of RBCs (1–82) and 44 units of PLTS (6–468). The greatest need for support was during the first 4 weeks postgrafting. A multivariate statistical analysis of 22 variables showed that RBC and PLT requirements increased with age. In addition, RBC requirements increased if the patient had isohemagglutinins against the marrow donor's RBC, i.e., if the marrow transplant was across a major ABO barrier. |
| Databáze: | OpenAIRE |
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