Chromoendoscopy and narrow-band imaging compared with high-resolution magnification endoscopy in Barrett's esophagus
Autor: | Jacques J. Bergman, Thomas Rabenstein, Lubbertus Baak, Jean Rey, Ralf Kiesslich, Paul Fockens, Arnoud H. Van Oijen, Fiebo J.W. ten Kate, Wouter L. Curvers, Krish Ragunath, Pieter Scholten, Uwe Seitz |
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Přispěvatelé: | Gastroenterology and Hepatology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, CCA -Cancer Center Amsterdam, Pathology |
Rok vydání: | 2007 |
Předmět: |
Male
medicine.medical_specialty Esophageal Neoplasms High resolution Indigo Carmine Gastroenterology Chromoendoscopy chemistry.chemical_compound Barrett Esophagus Esophagus Internal medicine medicine Humans Coloring Agents Acetic Acid Aged Aged 80 and over Observer Variation Narrow-band imaging Mucous Membrane Hepatology business.industry Reproducibility of Results Middle Aged medicine.disease Image Enhancement Magnification endoscopy medicine.anatomical_structure Indigo carmine chemistry Barrett's esophagus High Grade Intraepithelial Neoplasia Female Esophagoscopy Nuclear medicine business Precancerous Conditions |
Zdroj: | Gastroenterology, 134(3), 670-679. W.B. Saunders Ltd |
ISSN: | 1528-0012 0016-5085 |
Popis: | Background & Aims: The aim of this study was to compare magnified still images obtained with high-resolution white light endoscopy, indigo carmine chromoendoscopy, acetic acid chromoendoscopy, and narrow-band imaging to determine the best technique for use in Barrett's esophagus. Methods: We obtained magnified images from 22 areas with the 4 aforementioned techniques. Seven endoscopists with no specific expertise in Barretes esophagus or advanced imaging techniques and 5 international experts in this field evaluated these 22 areas for overall image quality, mucosal image quality, and vascular image quality. In addition, the regularity of mucosal and vascular patterns and the presence of abnormal blood vessels were evaluated, and this was correlated with histology. Results: The interobserver agreement for the 3 features of mucosal morphology with white light images ranged from kappa = 0.51 (95% confidence interval [CI]: 0.46-0.55) to kappa = 0.53 (95% CI: 0.50 - 0.57) for all observers, from kappa = 0.43 (95% CI: 0.33-0.54) to kappa = 0.53 (95% CI: 0.41-0.64) for experts, and from kappa = 0.51 (95% CI: 0.15 - 0.33) to kappa = 0.64 (95% CI: 0.58 - 0.70) for nonexperts. The interobserver agreement in these groups did not improve by adding one of the enhancement techniques. The yield for identifying early neoplasia with white light images was 86% for all observers, 90% for experts, and 84% for nonexperts. The addition of enhancement techniques did not improve the yield neoplasia. Conclusions: The addition of indigo carmine chromoendoscopy, acetic acid chromoendoscopy, or narrow-band imaging to white light images did not improve interobserver agreement or yield identifying early neoplasia in Barrett's esophagus |
Databáze: | OpenAIRE |
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