Primary Hepatic Squamous Cell Carcinoma With High Microsatellite Instability Shows Good Response to Programmed Cell Death 1 Inhibitor as Adjuvant Therapy

Autor: Hui Zhi Zhang, Chun Nian Wang, Yang Ke Hu, Sheng Dong Wu, Ding Zhang, Ke Wang, Jian Nan Sun, Guo Gao, Cai De Lu
Rok vydání: 2021
Předmět:
Zdroj: Hepatology. 74:1695-1697
ISSN: 1527-3350
0270-9139
DOI: 10.1002/hep.31737
Popis: Primary hepatic squamous cell carcinoma (SCC) is a rare, highly aggressive liver cancer that is associated with intrahepatic stone, liver cirrhosis, hepatic cyst, and Caroli's disease. At present, there are no settled therapy guidelines for primary hepatic SCC. Patients with successful surgical resection have a tumor-free survival of approximately 6 to 9 months.(1,2) Immune checkpoint inhibitors (ICIs) are a promising treatment for multiple tumor types, with significant efficacy and manageable toxicity.(3).
Databáze: OpenAIRE
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