Large-scale Digitoxin Intoxication
Autor: | A. H. Lely, C. H. J. Van Enter |
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Rok vydání: | 1970 |
Předmět: |
Male
Digoxin Gastrointestinal Diseases Digitoxin Neuritis Vision Disorders Feeding and Eating Disorders Muscular Diseases Tachycardia medicine Humans Medication Errors cardiovascular diseases Fatigue Aged General Environmental Science Depression business.industry Atrioventricular conduction Extreme fatigue General Engineering Arrhythmias Cardiac Nausea Papers and Originals General Medicine DIGITALIS INTOXICATION Heart Block Anesthesia General Earth and Planetary Sciences Female business medicine.drug |
Zdroj: | BMJ. 3:737-740 |
ISSN: | 1468-5833 0959-8138 |
Popis: | Because of an error in the manufacture of digoxin tablets a large number of patients took tablets that contained 0·20 mg. of digitoxin and 0·05 mg. of digoxin instead of the prescribed 0·25 mg. of digoxin. The symptoms are described of 179 patients who took these tablets and suffered from digitalis intoxication. Of these patients, 125 had taken the faultily composed tablets for more than three weeks. In 48 patients 105 separate disturbances in rhythm or in atrioventricular conduction were observed on the electrocardiogram. Extreme fatigue and serious eye conditions were observed in 95% of the patients. Twelve patients had a transient psychosis. Extensive ophthalmological observations indicated that the visual complaints were most probably caused by a transient retrobulbar neuritis. |
Databáze: | OpenAIRE |
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