Cor pulmonale in children: Review and etiological classification

Autor: Anne D. Morgan
Rok vydání: 1967
Předmět:
Zdroj: American Heart Journal. 73:550-562
ISSN: 0002-8703
DOI: 10.1016/0002-8703(67)90212-8
Popis: T he term “car pulmonale” is frequently misused and misunderstood. It comes from the Latin words COY, meaning heart, and pulmo, meaning lung. In a strict sense, “car pulmonale” refers to hypertrophy and failure of the right ventricle resulting from a primary lung disease. In a more liberal sense, the term may be used to describe an increased work load on the right ventricle from alterations in the pulmonary circulation, which may result from (1) diseases primarily affecting pulmonary ventilation and respiratory function, (2) diseases primarily affecting the pulmonary vasculature, or (3) primary cardiac diseases producing secondary alterations of the pulmonary vasculature. There has been much debate about a satisfactory definition for the term “car pulmonale” or “chronic car pulmonale,” but at a meeting of the World Health Organization in 1963,l it was decided to exclude primary cardiac diseases and define chronic car pulmonale as: “hypertrophy of the right ventricle resulting from diseases affecting the function and/or the structure of the lung, except when these pulmonary alterations are the result of diseases that primarily affect the left side of the heart or of congenital heart disease.” Thus, the term should include right ventricular hypertrophy resulting from any type of abnormality of respiratory structure and/or function. Cor pulmonale has received little attention in children. It is being recognized with increasing frequency, however, because of improved diagnostic methods and treatment. n’lany conditions which previously caused death frotn an acute respiratory infection in an early stage may now progress to the development of chronic lung disease. A classification of the etiological causes of car pulmonale is of more than academic interest because an understanding of the natural history and basic pathophysiology of the underlying respiratory disorder is essential for successful therapy. There is no recent physiologic or pathologic survey of car pulmonale in children. Therefore, this paper is a review and proposal of an etiological classification of car pulmonale in children based on the primary pathophysiology.
Databáze: OpenAIRE