Rotaviral gastrointestinal infection causing afebrile seizures in infancy and childhood

Autor: Thomas Lebby, Michael F. Contino, Edgardo Arcinue
Rok vydání: 1994
Předmět:
Zdroj: The American journal of emergency medicine. 12(1)
ISSN: 0735-6757
Popis: Diarrhea1 diseases in children often require hospitalization and can cause significant morbidity and mortality.’ An average of 500 children ages 1 month to 4 years die each year with diarrhea reported as a cause of death. Diarrhea1 deaths constitute an important and preventable fraction of postneonatal infant mortality in American children. ’ Although diarrhea1 deaths can be caused by many different causes, one etiological agent, Rotavirus, is believed to be responsible for the excess number of these deaths that occur in the winter months.2 This number is estimated to be 70 to 80 per year.‘,’ Associated causes of death in hospitalized children with acute diarrhea1 illness have been studied. The most commonly associated diagnoses were dehydration (34%), cardiac arrest (21%), respiratory failure (14%), prematurity (13%), shock (5%), malnutrition (2%), and bronchopneumonia (I%), conditions consistent with diarrhea and its complications as the main determinant of a fatal outcome.2,5 There are a few reports of central nervous system involvement associated with rotavirus gastrointestinal infections.3 Usitijiama et al describes a 9-month-old boy with suspected rotavirus encephalitis who developed afebrile tonic clonic seizures and delayed psychomotor development. Salmi et al described two patients, one whom developed fatal Reye’s syndrome and the other encephalitis with slow recovery.4 It is unclear if the etiology of the central nervous system involvement is the direct invasion of the virus into the central nervous system or a result of a coexisting viremia.3 We present three cases of afebrile seizures in patients with documented rotavirus gastrointestinal infections who presented to our institution in the winter of 1992.
Databáze: OpenAIRE