Epidemiology and cerebrovascular events related to cervical and intracranial arteries dissection: the experience of the city of Pisa
| Autor: | Giovanni Orlandi, L Ulivi, C Cravcenco, Ubaldo Bonuccelli, Michelangelo Mancuso, E Ferrari, M Maccarrone, Nicola Giannini, V. Montano |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Epidemiology Cervical Artery Vertebral artery Population Spontaneous dissection of cervical arteries Dermatology 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences 0302 clinical medicine medicine.artery Humans Medicine Age of Onset Cities education Stroke Aged Retrospective Studies Cerebrovascular events education.field_of_study business.industry Incidence Incidence (epidemiology) Intracranial Artery General Medicine Middle Aged medicine.disease Surgery Aortic Dissection Cerebrovascular Disorders Psychiatry and Mental health Dissection Italy Cervical Vertebrae Female Neurology (clinical) Internal carotid artery business 030217 neurology & neurosurgery |
| Zdroj: | Neurological Sciences. 38:1985-1991 |
| ISSN: | 1590-3478 1590-1874 |
| DOI: | 10.1007/s10072-017-3084-5 |
| Popis: | Spontaneous dissection of cervical arteries (sCAD) is a major cause of ischemic stroke in young patients, with an incidence varying from 1.7 to 3/100,000/year for extracranial internal carotid artery (ICAD) and 1 to 1.9/100,000/year for extracranial vertebral artery (VAD). Reliable epidemiological data on stroke incidence related to sCAD are scarce in Italy. This study aims to evaluate the incidence, clinical features, and outcome of cerebrovascular events related to sCAD and spontaneous intracranial arteries dissections (sIAD) in the city of Pisa (Italy). We retrospectively analyzed consecutive patients admitted between December 1997 and June 2015 with a diagnosis of stroke, TIA, or Bernard-Horner syndrome due to acute cervical or intracranial artery dissection. Considering that our hospital collects presumptively all patients hospitalized with sCAD coming from the referral geographical area, data may provide a good approximation to real incidence of sCAD in our population. Clinical and radiological features, acute treatment and outcome were collected. Seventy-seven cases were included (mean age 48.1±10.4 years, range 23-77,72.7% males), 66 residents in the district of Pisa. Crude incidence rate of cerebrovascular events due to intra or extracranial dissection was 1.88/100,000/year. The incidence of ICAD was 0.80/100,000/year and 0.43/100,000/year for VAD. Stroke occurred in 76.6% of patients. VAD was more prone to cause ischemic stroke and present with cervical pain or focal signs (p |
| Databáze: | OpenAIRE |
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