Evaluation of hypoglycemic and antihyperglycemic effects of Datura metel (Linn.) seeds in normal and alloxan-induced diabetic rats
| Autor: | Srinivas Nammi, R. V. Krishna Rao, N. Koteswara Rao, B. V. Krishna Murthy, Akula Annapurna, M.K Kota |
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| Rok vydání: | 2004 |
| Předmět: |
Blood Glucose
Male Dose dependence Pharmacognosy Biological fluid Diabetes Mellitus Experimental chemistry.chemical_compound Diabetes mellitus Alloxan Drug Discovery medicine Animals Hypoglycemic Agents Rats Wistar Pharmacology biology Traditional medicine business.industry medicine.disease biology.organism_classification Rats chemistry Seeds Datura Drug Evaluation Female Plant Preparations Datura metel business Phytotherapy |
| Zdroj: | Journal of Ethnopharmacology. 91:95-98 |
| ISSN: | 0378-8741 |
| DOI: | 10.1016/j.jep.2003.12.010 |
| Popis: | The seed powder of Datura metel was tested for its hypoglycemic activity in normal and alloxan-induced diabetic rats. Graded doses (25, 50 and 75 mg/kg, p.o.) of the seed powder when given to both normal and diabetic rats produced significant reduction in blood glucose at the 8 h. The effect was found to be dose dependent with all treatments at the doses administered. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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