Imaging-Based Treatment Adaptation in Radiation Oncology
| Autor: | Esther G.C. Troost, Daniela Thorwarth, Wim J.G. Oyen |
|---|---|
| Přispěvatelé: | Radiotherapie, RS: GROW - Oncology, RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
theranostics PET/CT medicine.medical_treatment Rare cancers Radboud Institute for Molecular Life Sciences [Radboudumc 9] Neoplasms medicine Medical imaging Humans Radiology Nuclear Medicine and imaging Image-guided radiation therapy PET-CT medicine.diagnostic_test business.industry Magnetic resonance imaging Magnetic Resonance Imaging Molecular Imaging Radiation therapy Functional imaging Positron emission tomography Positron-Emission Tomography Radiation Oncology functional MRI Radiology functional CT Nuclear medicine business Tomography X-Ray Computed Preclinical imaging |
| Zdroj: | The Journal of Nuclear Medicine (1978), 56, 1922-9 Journal of Nuclear Medicine 56(2015)12, 1922-1929 The Journal of Nuclear Medicine (1978), 56, 12, pp. 1922-9 Journal of Nuclear Medicine, 56(12), 1922-1929. Society of Nuclear Medicine and Molecular Imaging |
| ISSN: | 1535-5667 0161-5505 |
| Popis: | Item does not contain fulltext In many tumor types, significant effort is being put into patient-tailored adaptation of treatment to improve outcome and preferably reduce toxicity. These opportunities first arose with the introduction of modern irradiation techniques (e.g., intensity-modulated radiotherapy) combined with functional imaging for more precise delineation of target volume. On the basis of functional CT, MRI, and PET results, radiation target volumes are altered during the course of treatment, or subvolumes inside the primary tumor are defined to enhance the dosing strategy. Moreover, the probability of complications to normal tissues is predicted using anatomic or functional imaging, such as in the use of CT or PET to predict radiation pneumonitis. Besides focusing, monitoring, and adapting photon therapy for solid tumors, PET also has a role in verifying proton-beam therapy. This article discusses the current state and remaining challenges of imaging-based treatment adaptation in radiation oncology. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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