Quetiapine adverse events in older adults in Australia
| Autor: | Najwan El-Saifi, Wendy Moyle, Cindy Jones |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Gerontology
Adult Male medicine.medical_specialty Adolescent Drug-Related Side Effects and Adverse Reactions medicine.medical_treatment 030226 pharmacology & pharmacy Severity of Illness Index 03 medical and health sciences Quetiapine Fumarate Young Adult 0302 clinical medicine Risk Factors Severity of illness Odds Ratio Medicine Humans 030212 general & internal medicine Young adult Adverse effect Prospective cohort study Psychiatry Antipsychotic Aged Community and Home Care Aged 80 and over Chi-Square Distribution business.industry Age Factors Australia General Medicine Odds ratio Middle Aged Quetiapine Female Geriatrics and Gerontology business Chi-squared distribution medicine.drug Antipsychotic Agents |
| Zdroj: | Australasian journal on ageing. 35(4) |
| ISSN: | 1741-6612 |
| Popis: | Aim To characterise quetiapine reported adverse drug events (ADEs) in older Australians in terms of type, frequency, severity and outcome, and to compare these characteristics with those of younger Australians. Methods Basic descriptive analyses were used to examine patient characteristics. The characteristics of reported ADEs were compared between older and younger Australians using odds ratios and chi-squared tests. Results The most frequently reported ADEs in older people were nervous system disorders (23.7%). There were significantly more reports of skin and subcutaneous ADEs and hepatobiliary ADEs for older people than for younger people. More severe ADEs were reported in older people with death more likely to occur in older than in younger people Conclusion Significant differences between older and younger people in terms of reported ADEs, severity and mortality were found. There is a need for further prospective studies in older people on quetiapine to confirm the findings of this study. |
| Databáze: | OpenAIRE |
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