A Solid Phase C1q Enzyme Assay for Circulating Immune Complexes Adapted for Routine Clinical Laboratory Testing
| Autor: | Anne L. Vahey, Mark Robinson, Robert J. Marder, Karen K. James |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Antigen-Antibody Complex
Time Factors Complement Activating Enzymes Urology chemical and pharmacologic phenomena Laboratory testing Immunoenzyme Techniques Immune system Antibody Specificity immune system diseases medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases medicine.diagnostic_test biology business.industry Complement C1q Temperature General Medicine Molecular biology Enzyme assay Antibodies Anti-Idiotypic Biochemistry Immunoglobulin G Immunoassay biology.protein business |
| Zdroj: | American Journal of Clinical Pathology. 80:445-452 |
| ISSN: | 1943-7722 0002-9173 |
| Popis: | An assay for circulating immune complexes (CIC) that is adaptable to a routine clinical laboratory is described. This solid phase C1q (SP C1q) enzyme immunoassay (EIA) uses commercially available reagents and is reproducible with CV% of less than 20% in the abnormal range. We also demonstrate the specificity of the assay for detecting clinically relevant dsDNA-anti-DNA immune complexes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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