Fatal case of bilateral internal jugular vein thrombosis following IVIg infusion in an adolescent girl treated for ITP
| Autor: | Pui Ying Iroh Tam, Sat Kiran Grewal, Matthew W. Richardson |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Metrorrhagia Adolescent Deep vein Brain Edema Ethinyl Estradiol Dexamethasone Fatal Outcome hemic and lymphatic diseases medicine Humans Mannitol Thrombolytic Therapy Obesity Myocardial infarction Infusions Intravenous Internal jugular vein Thrombectomy Venous Thrombosis Purpura Thrombocytopenic Idiopathic Anemia Iron-Deficiency Heparin business.industry Vascular disease Anticoagulants Immunoglobulins Intravenous Hematology medicine.disease Combined Modality Therapy Thrombocytopenic purpura Thrombosis Surgery Venous thrombosis medicine.anatomical_structure Anesthesia cardiovascular system Female Jugular Veins Norethindrone business medicine.drug |
| Zdroj: | American Journal of Hematology. 83:323-325 |
| ISSN: | 1096-8652 0361-8609 |
| DOI: | 10.1002/ajh.21107 |
| Popis: | Intravenous immunoglobulin (IVIg) is often used as therapy in immune-mediated diseases and is generally considered a safe therapeutic agent. However, thrombotic complications such as myocardial infarction and deep vein thrombosis have been reported, although primarily in older adults. We describe a 13-year-old girl who received one dose of IVIg for immune thrombocytopenic purpura and developed fatal bilateral jugular venous thromboses. This is the first known case of IVIg-associated thrombosis in an adolescent and also the first report describing internal jugular vein thrombosis associated with IVIg infusion. We identify additional risks that may potentiate the agent's thrombotic risk. |
| Databáze: | OpenAIRE |
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