Pseudoepitheliomatous keratotic and micaceous balanitis treated with topical 5-fluorouracil and liquid nitrogen
Autor: | S. K. Ng, K J L Choo, C S Sim, S W N Cheng |
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Rok vydání: | 2017 |
Předmět: |
Pathology
medicine.medical_specialty business.industry Verrucous carcinoma Hyperkeratosis Glans penis Dermatology Papillomatosis medicine.disease 030207 dermatology & venereal diseases 03 medical and health sciences Foreskin 0302 clinical medicine medicine.anatomical_structure Dysplasia 030220 oncology & carcinogenesis medicine medicine.symptom business Parakeratosis Pseudoepitheliomatous keratotic and micaceous balanitis |
Zdroj: | Clinical and Experimental Dermatology. 42:424-426 |
ISSN: | 0307-6938 |
DOI: | 10.1111/ced.13072 |
Popis: | Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is an uncommon premalignant condition involving the glans penis. We report the case of an 86-year-old man who presented with phimosis and pain on retracting his foreskin. He had previously undergone circumcision, which revealed a hyperkeratotic plaque with thin mica-like scales involving his glans penis. Histology of the lesion showed hyperkeratosis, parakeratosis, epidermal acanthosis and papillomatosis with no evidence of dysplasia. Immunohistochemistry for human papillomavirus was negative. The patient was treated with topical 5-fluorouracil and liquid nitrogen with clinical improvement. He is now under long-term surveillance for verrucous carcinoma and squamous cell carcinoma. |
Databáze: | OpenAIRE |
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