Distribution of 14C-formaldehyde after pulpotomy with formocresol

Autor:	Thomas R. Dirksen, H K Shoaf, Gary M. Whitford, Myers Dr, K. E. Reynolds, David H. Pashley
Rok vydání:	1978
Předmět:	Male Time Factors business.industry Chemistry Pulpotomy Formaldehyde Formocresols Dentistry Haplorhini Macaca mulatta Absorption Iodine Radioisotopes chemistry.chemical_compound Animals Autoradiography Female Carbon Radioisotopes business General Dentistry Formaldehyde metabolism
Zdroj:	The Journal of the American Dental Association. 96:805-813
ISSN:	0002-8177
DOI:	10.14219/jada.archive.1978.0187
Popis:	Pulpotomies were performed on rhesus monkeys with use of formocresol to determine if there was uptake of 14C-formaldehyde into the systemic circulation after formocresol pulpotomies. Five-minute exposure of pulpal tissue to the 14C-formocresol resulted in the systemic absorption of approximately 1% of the dose. Two hours of exposure of pulp tissue to the 14C-formocresol did not increase the systemic absorption. Multiple sequential pulpotomies resulted in proportionately higher systemic absorption of 14C-formaldehyde. Application of 131I to pulpotomy sites indicated that formocresol compromises the microcirculation of the dental pulp. Autoradiography disclosed extensive concentrations of 14C-formaldehyde in the pulp, dentin, periodontal ligament, and bone.
Databáze:	OpenAIRE
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