Additional file 1: Figure S1. of Analysis of monocyte infiltration in MPTP mice reveals that microglial CX3CR1 protects against neurotoxic over-induction of monocyte-attracting CCL2 by astrocytes

Autor: Parillaud, Vincent, Lornet, Guillaume, Monnet, Yann, Anne-Laure Privat, Haddad, Andrei, Brochard, Vanessa, Bekaert, Amaury, Chanville, Camille De, Hirsch, Etienne, Combadière, Christophe, Hunot, Stéphane, Lobsiger, Christian
Rok vydání: 2017
Předmět:
DOI: 10.6084/m9.figshare.c.3721690_d2.v1
Popis: Global neuroinflammation and neurodegeneration in the substantia nigra of acute MPTP model mice. (A-C) Immunohistochemical stainings (anti-TH; brown) of DA neuronal degeneration at 2d (B) and loss at 7d (C) after acute MPTP intoxication in wild-type mice (C57BL/6J). Quantification shows the expected stable loss of around 30% of DA neurons (11,680 +/− 240, saline, n = 3; 8410 +/− 440, MPTP, n = 10) (28% loss; P
Databáze: OpenAIRE