The early and late efficacy of single-pass fractional carbondioxide laser, fractional radiofrequency, and their combination in acne scars: A prospective, split-face, single-blinded, controlled clinical study
| Autor: | Recep Dursun, Nida Kaçar, Şule Subaşi Gökşin, Merve Akbay |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
vitiligo
tetracaine patient satisfaction medicine.medical_treatment Fractional laser Clinical study 030207 dermatology & venereal diseases 0302 clinical medicine fractional radiofrequency therapy Acne Vulgaris Medicine pain Prospective Studies Acne sunscreen clinical article atrophic scar treatment lichen planus adult steroid immunosuppressive treatment General Medicine hypertrophic scar psoriasis keloid Treatment Outcome female 030220 oncology & carcinogenesis lidocaine young adult disease severity Laser Therapy topical anesthesia prospective study Single pass medicine.medical_specialty sex difference photosensitivity Dermatology scar Article 03 medical and health sciences Cicatrix Patient satisfaction radiofrequency clinical examination male Effective treatment Humans controlled study human Acne scars acne carbondioxide laser single blind procedure dermatitis combination Radiofrequency Ablation therapy controlled clinical trial business.industry Triticum vulgare extract clinical effectiveness filler face visual analog scale isotretinoin bleeding tendency Carbon dioxide laser medicine.disease 2 phenoxyethanol low level laser therapy radiofrequency therapy Surgery connective tissue disease Lasers Gas fractional laser business edema erythema |
| Popis: | We investigated the effectiveness of fractional carbon dioxide laser (FCO2) vs fractional radiofrequency (FRF) and FCO2 vs FRF plus FCO2 combination in the treatment of acne scars. Twenty-seven patients were included. Scar severity was scored with “Echelle d'évaluation clinique des cicatrices d'acné” (ECCA) by a dermatologist blinded to treatment. FCO2 and FRF were administered to the right and left halves of the patients' faces, respectively, at the first three visits, once a month. At the fourth visit, FCO2 was administered to both sides. Last evaluation was performed 6 months after the last treatment. Mean ECCA scores for both face halves decreased gradually at each visit compared with Visit-1; however, the effect size of decrease was higher in the right half of the face and in terms of gender differences was higher in women for both sides that the difference was more pronounced for the FRF side. There was no statistically significant change in the mean VAS patient satisfaction scores in the following visits compared with Visit-2 on both halves (P >.05). Side effects were similar; but lasted longer in the FCO2 side. Both FCO2 and FRF are effective treatment methods in the treatment of atrophic acne scars. Combining FCO2 to FRF improves patient satisfaction. FRF may achieve better results in women compared with men. To our knowledge the study is unique prospective, controlled clinical study comparing the efficacy of FCO2 and FRF plus FCO2 combination treatments. © 2020 Wiley Periodicals LLC. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|