Preparation of carbon dot-based ratiometric fluorescent probes for cellular imaging from Curcuma longa
| Autor: | Insik In, Sung Young Park, Zihnil Adha Islamy Mazrad, Eun Bi Kang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Cell Survival
Surface Properties Biophysics Analytical chemistry Quantum yield Nanoparticle Biocompatible Materials 02 engineering and technology Polyethylene glycol 010402 general chemistry 01 natural sciences KB Cells Madin Darby Canine Kidney Cells chemistry.chemical_compound Curcuma Dogs X-ray photoelectron spectroscopy Quantum Dots PEG ratio Animals Humans Particle Size Fluorescent Dyes biology 021001 nanoscience & nanotechnology biology.organism_classification Fluorescence Carbon 0104 chemical sciences Spectrometry Fluorescence chemistry Chemistry (miscellaneous) Nanoparticles Amine gas treating 0210 nano-technology Nuclear chemistry |
| Zdroj: | Luminescence. 33:40-46 |
| ISSN: | 1522-7235 |
| DOI: | 10.1002/bio.3370 |
| Popis: | This work derived biocompatible and stable probes based on fluorescent nanoparticles (FNPs) from a natural source, Curcuma longa. The multi-color fluorescence emissions from carbonized Curcuma longa (C-FNPs) obtained through defined dehydration conditions are soluble in water and have a small particle size (~17 nm). The surface passivation with polyethylene glycol (PEG) capped with amine groups in FNPs (P-FNPs) generated a probe with a higher quantum yield and longer fluorescence lifetime than obtained with C-FNPs. The X-ray photoelectron spectroscopy and X-ray diffraction spectra confirmed the associated chemical moieties of C-FNPs and P-FNPs. Furthermore, the prepared material showed non-toxic effects with almost 100% cell viability, even at high concentrations. In conclusion, fluorescence sensors from natural sources may be useful for numerous biomedical research applications. |
| Databáze: | OpenAIRE |
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