Effects of age-related hearing loss and background noise on neuromagnetic activity from auditory cortex
| Autor: | Claire Salloum, Anja Roye, Claude Alain |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Sound localization
medicine.medical_specialty Hearing loss Cognitive Neuroscience Neuroscience (miscellaneous) Audiology Auditory cortex 050105 experimental psychology lcsh:RC321-571 Background noise 03 medical and health sciences Cellular and Molecular Neuroscience symbols.namesake 0302 clinical medicine Developmental Neuroscience otorhinolaryngologic diseases medicine auditory cortex inhibition (psychology) 0501 psychology and cognitive sciences Original Research Article Sound pressure lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry hearing loss MEG medicine.diagnostic_test aging 05 social sciences Magnetoencephalography Noise Gaussian noise symbols medicine.symptom Psychology 030217 neurology & neurosurgery Neuroscience |
| Zdroj: | Frontiers in Systems Neuroscience, Vol 8 (2014) Frontiers in Systems Neuroscience |
| ISSN: | 1662-5137 |
| DOI: | 10.3389/fnsys.2014.00008 |
| Popis: | Aging is often accompanied by hearing loss, which impacts how sounds are processed and represented along the ascending auditory pathways and within the auditory cortices. Here, we assess the impact of mild binaural hearing loss on the older adults' ability to both process complex sounds embedded in noise and to segregate a mistuned harmonic in an otherwise periodic stimulus. We measured auditory evoked fields (AEFs) using magnetoencephalography while participants were presented with complex tones that had either all harmonics in tune or had the third harmonic mistuned by 4 or 16% of its original value. The tones (75 dB sound pressure level, SPL) were presented without, with low (45 dBA SPL), or with moderate (65 dBA SPL) Gaussian noise. For each participant, we modeled the AEFs with a pair of dipoles in the superior temporal plane. We then examined the effects of hearing loss and noise on the amplitude and latency of the resulting source waveforms. In the present study, results revealed that similar noise-induced increases in N1m were present in older adults with and without hearing loss. Our results also showed that the P1m amplitude was larger in the hearing impaired than in the normal-hearing adults. In addition, the object-related negativity (ORN) elicited by the mistuned harmonic was larger in hearing impaired listeners. The enhanced P1m and ORN amplitude in the hearing impaired older adults suggests that hearing loss increased neural excitability in auditory cortices, which could be related to deficits in inhibitory control. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|