Effect of lung resection on pleuro-pulmonary mechanics and fluid balance
| Autor: | Giuseppe Miserocchi, Dario Bovio, Caterina Salito, Michele Salati, Alessandro Brunelli, G. Orsetti, Andrea Aliverti |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Lung Neoplasms Physiology Statistics as Topic Aged Aged 80 and over Female Humans Lung Lung Compliance Middle Aged Pleura Positive-Pressure Respiration Respiratory Mechanics Water-Electrolyte Balance Neuroscience (all) Respiratory physiology 030204 cardiovascular system & hematology Pulmonary compliance Resection 03 medical and health sciences 0302 clinical medicine 80 and over medicine Lung cancer Pulmonary mechanics Pulmonary gas pressures business.industry General Neuroscience respiratory system medicine.disease respiratory tract diseases Surgery medicine.anatomical_structure 030228 respiratory system Lung resection business |
| Zdroj: | Respiratory Physiology & Neurobiology. 221:35-40 |
| ISSN: | 1569-9048 |
| Popis: | The aim of the study was to determine in human patients the effect of lung resection on lung compliance and on pleuro-pulmonary fluid balance. Pre and post-operative values of compliance were measured in anesthetized patients undergoing resection for lung cancer (N=11) through double-lumen bronchial intubation. Lung compliance was measured for 10-12 cm H2O increase in alveolar pressure from 5 cm H2O PEEP in control and repeated after resection. No air leak was assessed and pleural fluid was collected during hospital stay. A significant negative correlation (r(2)=0.68) was found between compliance at 10 min and resected mass. Based on the pre-operative estimated lung weight, the decrease in compliance following lung resection exceeded by 10-15% that expected from resected mass. Significant negative relationships were found by relating pleural fluid drainage flow to the remaining lung mass and to post-operative lung compliance. Following lung re-expansion, data suggest a causative relationship between the decrease in compliance and the perturbation in pleuro-pulmonary fluid balance. |
| Databáze: | OpenAIRE |
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