Assessment of tracheal intubation in children after induction with propofol and different doses of remifentanil
| Autor: | D.A. Hill, C. M. Wilson, J. M. Blair, J.P.H. Fee |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Male
Epinephrine medicine.medical_treatment Remifentanil Hemodynamics Blood Pressure Norepinephrine Piperidines Heart Rate Heart rate Intubation Intratracheal medicine Humans Intubation Respiratory system Child Propofol Dose-Response Relationship Drug Laryngoscopy business.industry Respiration Tracheal intubation Analgesics Opioid Anesthesiology and Pain Medicine Blood pressure Child Preschool Anesthesia Female business Anesthetics Intravenous medicine.drug |
| Zdroj: | Anaesthesia. 59:27-33 |
| ISSN: | 1365-2044 0003-2409 |
| DOI: | 10.1111/j.1365-2044.2004.03524.x |
| Popis: | Tracheal intubating conditions were assessed in 112 children after induction of anaesthesia with propofol and remifentanil 1.0, 2.0 or 3.0 micro g.kg-1. Subjects in a control group were given propofol and mivacurium 0.2 mg.kg-1. Haemodynamic and respiratory parameters were recorded. Plasma catecholamine levels were measured in a subgroup of 40 children. Intubating conditions were acceptable in 14/28 (50%), 18/26 (69%) and 22/27 (82%) in those subjects given remifentanil 1.0, 2.0 or 3.0 micro g.kg-1, respectively, and in 27/28 (96%) of the control group. Intubating conditions in subjects given remifentanil 3.0 micro g.kg-1 were better than in those given remifentanil 1.0 micro g.kg-1 (p < 0.05). There were no significant differences in intubating conditions between those given remifentanil 3.0 micro g.kg-1 and the control group. Systolic blood pressure and heart rate increased in response to tracheal intubation in subjects given remifentanil 1.0 micro g.kg-1 and in the control group (p < 0.05). Time to resumption of spontaneous respiration was prolonged in subjects given remifentanil 3.0 micro g.kg-1 (p < 0.001). In conclusion, remifentanil 2 micro g.kg-1 provides acceptable intubating conditions and haemodynamic stability without prolonging the return of spontaneous respiration. |
| Databáze: | OpenAIRE |
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