Comparison of left atrial size and function in hypertrophic cardiomyopathy and in Fabry disease with left ventricular hypertrophy

Autor:	María C. Saccheri, Tomás F. Cianciulli, Juan Gagliardi, Jorge A. Lax, Aadelfa, Luis A. Morita, Wilde Challapa Licidio, Martín A Beck
Rok vydání:	2018
Předmět:	Adult Male medicine.medical_specialty Contraction (grammar) Cardiomyopathy 030204 cardiovascular system & hematology Left ventricular hypertrophy Ventricular Function Left 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases 030212 general & internal medicine Heart Atria Prospective Studies business.industry Hypertrophic cardiomyopathy Reproducibility of Results Atrial fibrillation Cardiomyopathy Hypertrophic Middle Aged medicine.disease Fabry disease Pathophysiology Echocardiography Doppler Color cardiovascular system Cardiology Fabry Disease Myocardial fibrosis Atrial Function Left Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business
Zdroj:	Echocardiography (Mount Kisco, N.Y.). 35(5)
ISSN:	1540-8175
Popis:	BACKGROUND Fabry disease (FD) and hypertrophic cardiomyopathy (HCM) are two diseases with a different pathophysiology, both cause left ventricular hypertrophy (LVH) and myocardial fibrosis. Although remodeling and systolic dysfunction of the left atrium (LA) are associated with atrial fibrillation and stroke in HCM, changes in the size and function of the LA have not been well studied in FD with LVH. METHODS The following groups were studied prospectively, and their respective findings compared: 19 patients with non-obstructive HCM (Group I), 20 patients with a diagnosis of Fabry cardiomyopathy (Group II), and 20 normal subjects matched for sex and age (Group III). Left ventricular mass index was measured using Devereux' formula, left atrial volume with Simpson's biplane method and left atrial mechanical function, including strain and strain rate, was measured using the speckle tracking technique. Strain and strain rate of the reservoir were measured during the three phases: reservoir (SR S), passive conduit (SR E) and atrial contraction (SR A). RESULTS Patients with HCM had a larger left atrial volume than patients with FD (48.16 ± 14.3 mL/m2 vs 38.9 ± 14.9 mL/m2 respectively, P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::060420dbd6884c25d6a825a31477b845 https://pubmed.ncbi.nlm.nih.gov/29457264 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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