Prevalence and characteristics of pharyngeal group A beta-hemolytic streptococci in US Navy recruits receiving benzathine penicillin prophylaxis
| Autor: | Kaplan El, Linz Pe, Alfred D. Heggie, Bernard Boxerbaum, Han Dp, Michael R. Jacobs |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Serotype
Male medicine.medical_specialty medicine.drug_class Streptococcus pyogenes Penicillin G Benzathine Antibiotics Prevalence medicine.disease_cause Drug Hypersensitivity Throat Internal medicine Streptococcal Infections medicine Immunology and Allergy Humans Serotyping business.industry Streptococcus Pharynx Pharyngitis United States Infectious Diseases medicine.anatomical_structure Military Personnel Immunology medicine.symptom business |
| Zdroj: | The Journal of infectious diseases. 166(5) |
| ISSN: | 0022-1899 |
| Popis: | US military recruits receive benzathine penicillin prophylaxis because of endemicity of group A beta-hemolytic streptococcal (GABHS) infections. GABHS prevalence in Navy recruits receiving single-dose benzathine penicillin prophylaxis was assessed during spring and fall 1989 by culturing throat specimens from randomly selected groups of approximately 230 men before and 2, 4, and 7 weeks after prophylaxis and from men with pharyngitis diagnosed at sick call. Of 60 GABHS isolates, 75% were serotype M-3. The pharyngitis rate increased from 0.18% in the spring to 1.55% in the fall with a concurrent increase in serotype M-3 prevalence from 35% to 91%. The GABHS prevalence rate was three- to fourfold lower after prophylaxis. There were no cases of acute rheumatic fever (ARF) despite predominance of M-3, a rheumatogenic serotype. It was concluded that penicillin prophylaxis continues to be effective for control of GABHS infections and prevention of ARF in Navy recruits. |
| Databáze: | OpenAIRE |
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