Evoked Potentials in Patients with Chronic Respiratory Insufficiency

Autor: Katsumasa Tokunaga, Shigehiro Imamura, Isao Hashimoto, Shuji Nakano, Sadatoshi Tsuji
Rok vydání: 1997
Předmět:
Zdroj: Internal Medicine. 36:270-275
ISSN: 1349-7235
0918-2918
Popis: P300, somatosensory evoked potential (SEP) and brainstem auditory evoked potential (BAEP) are widely used neurophysiological methods for objectively evaluating cognitive, somatosensory and brainstem auditory functions. We studied the P300, SEP and B AEP in 17 patients with chronic respiratory insufficiency (PaO2:58.2±7.0 mmHg; mean ± SD) and 15 age-matched healthy subjects (PaO2: 84.4 ± 11.3 mmHg). The latency and amplitude of P300, the N9 latency, N9-N13 and N13-N20 interpeak latencies (IPL) in SEP, wave I latency and I-VIPL in B AEP were compared between the patients and controls. The P300 latency, N9-N13 and N13-N20 IPLs in SEP in the patients were significantly prolonged compared to the controls. In contrast, the amplitude of P300, N9 latency in SEP, wave I latency and I-V IPL in B AEP were not significantly different between the patients and controls. These results suggest that chronic respiratory insufficiency influences the cognitive and somatosensory functions, and indicate that there is a selective vulnerability of evoked potentials to this condition.(Internal Medicine 36: 270-275, 1997)
Databáze: OpenAIRE