Prevention of biofilm formation by dairy products and N-Acetylcysteine on voice prostheses in an artificial throat
| Autor: | Ietse Stokroos, Leonora Q. Schwandt, Henk J. Busscher, Henny C. van der Mei, Ranny van Weissenbruch, Frans W. J. Albers |
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| Přispěvatelé: | Faculteit Medische Wetenschappen/UMCG, Man, Biomaterials and Microbes (MBM), Personalized Healthcare Technology (PHT) |
| Rok vydání: | 2004 |
| Předmět: |
Prosthesis-Related Infections
Cultured Milk Products integrity of biofilm Bacterial Adhesion Microbiology law.invention Probiotic law Streptococcal Infections Throat Humans Medicine Expectorants lifetime business.industry Candidiasis voice prostheses YEASTS Biofilm food and beverages MICROSCOPY IN-VITRO General Medicine Staphylococcal Infections Voice prosthesis Acetylcysteine medicine.anatomical_structure probiotics Otorhinolaryngology Biofilms BACTERIA Microscopy Electron Scanning Larynx Artificial valve design business |
| Zdroj: | Acta oto-Laryngologica, 124(6), 726-731 |
| ISSN: | 1651-2251 0001-6489 |
| DOI: | 10.1080/00016480410022516 |
| Popis: | Objective - To evaluate the preventive effect of buttermilk, Yakult Light fermented milk drink and N-acetylcysteine on biofilm formation on voice prostheses in vitro.Material and Methods - Groningen button and Provox(R) 2 voice prostheses were inoculated with a mixture of bacteria and yeasts isolated from previously explanted Groningen button voice prostheses. After 5 h, separate throats were flushed with buttermilk, Yakult Light fermented milk drink, N-acetylcysteine or phosphate-buffered saline, which served as a control. After 7 days, the microflora on each voice prosthesis was determined.Results - On Groningen button voice prostheses, buttermilk, Yakult Light fermented milk drink and N-acetylcysteine all reduced the amount of both bacteria and yeasts. On Provox(R)2 voice prostheses, buttermilk, Yakult Light fermented milk drink and N-acetylcysteine reduced the amount of bacteria but, conversely, increased the amount of yeasts.Conclusion - These in vitro experiments demonstrate that biofilm formation on voice prostheses is reduced in an artificial throat by the use of buttermilk, Yakult Light fermented milk drink and N-acetylcysteine. However, the structural differences between the type of voice prostheses may influence the ultimate effects. |
| Databáze: | OpenAIRE |
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