Ranitidine-induced acute interstitial nephritis in a cadaveric renal allograft
| Autor: | Judy A. King, Barry J. Browne, Cindy Op't Holt, Osemwegie E. Emovon |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Interstitial nephritis Ranitidine Biopsy medicine Cadaver Eosinophilia Humans Kidney medicine.diagnostic_test business.industry medicine.disease Kidney Transplantation Transplantation surgical procedures operative medicine.anatomical_structure Nephrology Acute Disease Nephritis Interstitial Female medicine.symptom Complication business Kidney disease medicine.drug |
| Zdroj: | American journal of kidney diseases : the official journal of the National Kidney Foundation. 38(1) |
| ISSN: | 1523-6838 |
| Popis: | Ranitidine frequently is used for preventing peptic ulceration after renal transplantation. This drug occasionally has been associated with acute interstitial nephritis in native kidneys. There are no similar reports with renal transplantation. We report a case of ranitidine-induced acute interstitial nephritis in a recipient of a cadaveric renal allograft presenting with acute allograft dysfunction within 48 hours of exposure to the drug. The biopsy specimen showed pathognomonic features, including eosinophilic infiltration of the interstitial compartment. Allograft function improved rapidly and returned to baseline after stopping the drug. © 2001 by the National Kidney Foundation, Inc . |
| Databáze: | OpenAIRE |
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