Optical coherence tomography angiography characteristics of polypoidal choroidal vasculopathy
Autor: | Ala El Ameen, Alexandra Miere, Giuseppe Querques, Mayer Srour, Anne Sikorav, Eric H. Souied, Olivia Zambrowski, Oudy Semoun |
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Přispěvatelé: | Srour, M., Querques, G., Semoun, O., El Ameen, A., Miere, A., Sikorav, A., Zambrowski, O., Souied, E. H. |
Rok vydání: | 2016 |
Předmět: |
Male
medicine.medical_specialty Pathology genetic structures Fundus Oculi Severity of Illness Index Retina Imaging Lesion 03 medical and health sciences Cellular and Molecular Neuroscience Polyps 0302 clinical medicine Ophthalmology medicine Humans Prospective Studies Fluorescein Angiography Prospective cohort study Aged Aged 80 and over Neovascularisation medicine.diagnostic_test Choroid business.industry Fundus photography Retinal Vessels Blood flow Middle Aged Fluorescein angiography Choroidal Neovascularization eye diseases Sensory Systems medicine.anatomical_structure Choroidal neovascularization Regional Blood Flow 030221 ophthalmology & optometry Female sense organs medicine.symptom business Tomography Optical Coherence 030217 neurology & neurosurgery Follow-Up Studies |
Zdroj: | British Journal of Ophthalmology. 100:1489-1493 |
ISSN: | 1468-2079 0007-1161 |
DOI: | 10.1136/bjophthalmol-2015-307892 |
Popis: | Purpose To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A). Methods Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral-domain OCT and OCT-A. Results Twelve eyes of 12 patients (mean age 72.6±10.5 years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyperflow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyperflow round structure, surrounded by a hypointense halo, and in 9/12 eyes (75%) a hypoflow round structure. Conclusions The OCT-A is a non-invasive imaging modality allowing the visualisation of different structures in PCV. The BVN is constantly clearly detected. The hypoflow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the BVN. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV. |
Databáze: | OpenAIRE |
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