Optical coherence tomography angiography characteristics of polypoidal choroidal vasculopathy

Autor: Ala El Ameen, Alexandra Miere, Giuseppe Querques, Mayer Srour, Anne Sikorav, Eric H. Souied, Olivia Zambrowski, Oudy Semoun
Přispěvatelé: Srour, M., Querques, G., Semoun, O., El Ameen, A., Miere, A., Sikorav, A., Zambrowski, O., Souied, E. H.
Rok vydání: 2016
Předmět:
Zdroj: British Journal of Ophthalmology. 100:1489-1493
ISSN: 1468-2079
0007-1161
DOI: 10.1136/bjophthalmol-2015-307892
Popis: Purpose To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A). Methods Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral-domain OCT and OCT-A. Results Twelve eyes of 12 patients (mean age 72.6±10.5 years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyperflow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyperflow round structure, surrounded by a hypointense halo, and in 9/12 eyes (75%) a hypoflow round structure. Conclusions The OCT-A is a non-invasive imaging modality allowing the visualisation of different structures in PCV. The BVN is constantly clearly detected. The hypoflow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the BVN. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV.
Databáze: OpenAIRE