Novel intracellular proteins associated with cellular vitamin D action

Autor: Jean Mayer, Giana Angelo, Richard J. Wood
Rok vydání: 2002
Předmět:
Zdroj: Nutrition reviews. 60(7 Pt 1)
ISSN: 0029-6643
Popis: Work with vitamin D-resistant New World primates has revealed novel cellular proteins involved in vitamin D action. An "intracellular vitamin D-binding protein" functions to bind vitamin D metabolites in the cell and enhances vitamin D action. By contrast, a "vitamin D response element-binding protein" inhibits vitamin D receptor binding to the DNA and is responsible for vitamin D resistance in New World primates.
Databáze: OpenAIRE