Urinary bladder malignant paraganglioma with vertebral metastasis: a case report with literature review
Autor: | Hai-De Gao, Ning Feng, Wen-Zhi Liu, Zhong-Lin Liu, Lu-Jing Shi, Xiang Li |
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Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: |
Pathology
medicine.medical_specialty medicine.medical_treatment Population Synaptophysin carcinoma Malignancy Cystectomy Thoracic Vertebrae surgery Paraganglioma neuroendocrine peptide medicine Malignant Paraganglioma Humans education Radionuclide Imaging education.field_of_study Urinary bladder Spinal Neoplasms business.industry Bone neoplasms Bone metastasis Technetium Middle Aged medicine.disease Prognosis Case Research medicine.anatomical_structure Oncology Urinary Bladder Neoplasms Phosphopyruvate Hydratase Thoracic vertebrae Chromogranin A malignant paraganglioma Female Radiology neuroendocrine tumors business Tomography X-Ray Computed |
Zdroj: | Chinese Journal of Cancer |
ISSN: | 1944-446X 1000-467X |
Popis: | Paraganglioma is a rare neuroendocrine neoplasm observed in patients of all ages, with an estimated incidence of 3/1,000,000 population. It has long been recognized that some cases are familial. The majority of these tumors are benign, and the only absolute criterion for malignancy is the presence of metastases at sites where chromaffin tissue is not usually found. Some tumors show gross local invasion and recurrence, which may indeed kill the patient, but this does not necessarily associate with metastatic potential. Here, we report a case of vertebral metastatic paraganglioma that occurred 19 months after the patient had undergone partial cystectomy for urinary bladder paraganglioma. We believe this to be a rarely reported bone metastasis of paraganglioma arising originally within the urinary bladder. In this report, we also provide a summary of the general characteristics of this disease, together with progress in diagnosis, treatment, and prognosis. |
Databáze: | OpenAIRE |
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