Determination of Allicin, S-Allylcysteine and Volatile Metabolites of Garlic in Breath, Plasma or Simulated Gastric Fluids
| Autor: | Thomas G. Hartman, Richard D. Hiserodt, Reginald J. Ruiz, J. Lech, Robert T. Rosen, Sharon L. Rosen, Elaine K. Fukuda, Zhengyi Zhou |
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| Rok vydání: | 2001 |
| Předmět: |
S-Adenosylmethionine
Chromatography Gas Antioxidant Allyl methyl sulfide medicine.medical_treatment Medicine (miscellaneous) Atmospheric-pressure chemical ionization Sulfides Mass spectrometry High-performance liquid chromatography Gas Chromatography-Mass Spectrometry chemistry.chemical_compound medicine Humans Cysteine Disulfides Garlic Chromatography High Pressure Liquid Plants Medicinal Nutrition and Dietetics Chromatography Allicin Plant Extracts food and beverages Sulfinic Acids Glutathione Gastrointestinal Contents Allyl Compounds Breath Tests chemistry Gas chromatography Allyl Sulfide |
| Zdroj: | The Journal of Nutrition. 131:968S-971S |
| ISSN: | 0022-3166 |
| DOI: | 10.1093/jn/131.3.968s |
| Popis: | Various components of garlic and aged garlic extract, including allicin, S-allylcysteine (SAC) and volatile metabolites of allicin were determined in breath, plasma and simulated gastric fluids by HPLC, gas chromatography (GC) or HPLC- and GC-mass spectrometry (MS). Data indicate that allicin decomposes in stomach acid to release allyl sulfides, disulfides and other volatiles that are postulated to be metabolized by glutathione and/or S-adenosylmethionine to form allyl methyl sulfide. SAC can be absorbed by the body and can be determined in plasma by HPLC or HPLC-MS using atmospheric pressure chemical ionization (APCI)-MS. |
| Databáze: | OpenAIRE |
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