Induction of fertile oestrus in the bitch using Deslorelin, a GnRH agonist

Autor: Alain Fontbonne, Christelle Navarro, A. Gérardin, F. Vannier, E. Fontaine, Fernando Mir, Maxime Albouy
Přispěvatelé: Biologie du Développement et Reproduction (BDR), Institut National de la Recherche Agronomique (INRA), Centre d'Etudes en Reproduction des Carnivores (CERCA), École nationale vétérinaire d'Alfort (ENVA), Biologie du développement et reproduction (BDR), Centre National de la Recherche Scientifique (CNRS)-École nationale vétérinaire d'Alfort (ENVA)-Institut National de la Recherche Agronomique (INRA)
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Theriogenology
Theriogenology, Elsevier, 2011, 76 (8), pp.1561-1566. ⟨10.1016/j.theriogenology.2011.06.031⟩
ISSN: 0093-691X
DOI: 10.1016/j.theriogenology.2011.06.031⟩
Popis: Oestrus induction in various canine breeds was attempted in 32 bitches. A group of 8 bitches were treated 80-160 d following their previous oestrus (G1) whereas a second group of 24 bitches (G2) were implanted 200-590 d following their previous oestrus. The treatment for each bitch consisted in one Deslorelin implant (Suprelorin® 4,7 mg, Virbac, France), inserted subcutaneously in the post-umbilical region. Ovulation, pregnancy rate and litter size were recorded. All bitches came in heat 4.3 ± 1.4 d after implantation (2-7 d). Ovulation was reported in 62.5% in G1 and 87.5% in G2. One bitch refused mating and since no AI was performed, she was not considered for further analysis. Pregnancy was obtained in 25% in G1 versus 78.3% in G2. Mean litter size was 6.7 ± 3.5 puppies (1-14). Luteal failure was suspected in 3 bitches, two that remained non-pregnant and one which aborted 58 d post-ovulation since the owner refused progesterone supplementation. Deslorelin implants can therefore be considered as a valuable alternative to induce fertile oestrus in bitches in anoestrus. Follow-up of the luteal phase is recommended, since some bitches might encounter luteal failure.
Databáze: OpenAIRE