S100B in bone marrow aspirates in healthy individuals and malignant melanoma patients
| Autor: | Ragnar S. Faye, Gunhild Mari Mælandsmo, Hanne K. Høifødt, Steinar Aamdal, Elisabeth Paus, Aasmund Berner, Øystein Fodstad |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Cancer Research Pathology medicine.medical_specialty Skin Neoplasms medicine.drug_class S100 Calcium Binding Protein beta Subunit Dermatology Monoclonal antibody Immune system Bone Marrow medicine Humans Blood test Nerve Growth Factors Stage (cooking) Melanoma Aged Aged 80 and over Sex Characteristics medicine.diagnostic_test business.industry S100 Proteins Middle Aged medicine.disease Log-rank test medicine.anatomical_structure Oncology Healthy individuals Female Bone marrow business |
| Zdroj: | Melanoma Research. 18:134-140 |
| ISSN: | 0960-8931 |
| DOI: | 10.1097/cmr.0b013e3282f623d9 |
| Popis: | The aim of this study was to evaluate S100B in bone marrow (BM) plasma from malignant melanoma patients. BM aspirates and peripheral blood (PB) plasma from 56 patients and BM aspirates from 29 healthy volunteers were collected. S100B was measured using an immune radiometric assay, which is a two-site sandwich assay based on monoclonal antibodies recognizing the beta-subunit. In the control population, the median S100B level in BM plasma was 9.0 microg/l (26 women and three men), an unexpectedly high value compared with the median S100B level in PB |
| Databáze: | OpenAIRE |
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