DFT insights into superelectrophilic activation of α,β-unsaturated nitriles and ketones in superacids
| Autor: | Alexander M. Genaev, George E. Salnikov, Konstantin Yu. Koltunov |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Organic & Biomolecular Chemistry. 20:6799-6808 |
| ISSN: | 1477-0539 1477-0520 |
| Popis: | Superelectrophilic activation of α,β-unsaturated carbonyl compounds and their isoelectronic analogs, proceeding normally under superacidic conditions, have led to a great variety of beneficial synthetic transformations. However, the essence of such activation is not yet fully recognized, while a number of alternative views on the subject have been discussed at length in the literature. Here, taking the example of virtual reactions of cinnamonitrile and benzalacetone with benzene, their feasible mechanistic variants, including multiple protonation (coordination to AlCl |
| Databáze: | OpenAIRE |
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