Effect of prior chemotherapy on hematopoietic stem cell mobilization
| Autor: | C D Ford, Finn Bo Petersen, Green Wf, S Warenski |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Oncology
Male medicine.medical_specialty medicine.medical_treatment Antigens CD34 Colony-Stimulating Factors Internal medicine Neoplasms Granulocyte Colony-Stimulating Factor medicine Humans Doxorubicin Prior Radiation Therapy Hematopoietic Stem Cell Mobilization Etoposide Retrospective Studies Transplantation Chemotherapy business.industry Age Factors Hematopoietic stem cell Hematology DNA Hematopoietic Stem Cells Chemotherapy regimen medicine.anatomical_structure Cross-Linking Reagents Immunology Female Stem cell business medicine.drug DNA Damage |
| Zdroj: | Bone marrow transplantation. 33(9) |
| ISSN: | 0268-3369 |
| Popis: | A number of studies have suggested that prior chemotherapy correlates negatively with the efficiency of hematopoietic stem cell mobilization. However, little data exist with regard to the relative effects of the specific chemotherapeutic drug classes. We retrospectively reviewed the records of 201 consecutive patients with nonmyeloid malignancies undergoing CD34+ cell mobilization with chemotherapy+granulocyte colony-stimulating factor (G-CSF). The number of prior chemotherapy courses correlated negatively with the peripheral CD34+ cell concentration (pCD34) on the first day of collection (P |
| Databáze: | OpenAIRE |
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