Extensive gene conversion between CCR2 and CCR5 in domestic cat (Felis catus)
| Autor: | W. van der Loo, Pedro J. Esteves, Joana Abrantes |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Genetics
CCR2 Receptors CCR5 Receptors CCR2 Molecular Sequence Data Immunology Protein domain Gene Conversion General Medicine Anatomy Biology Chemokine receptor Cats Extracellular Animals Amino Acid Sequence Gene conversion Felis catus Molecular Biology Pathogen Phylogeny Genetics (clinical) Homogenization (biology) |
| Zdroj: | International Journal of Immunogenetics. 34:321-324 |
| ISSN: | 1744-313X 1744-3121 |
| Popis: | Summary Homogenization of the CC-motif chemokine receptors CCR2 and CCR5 of cat (Felis catus) is documented and shown to be the outcome of gene conversion within the feline lineage. All regions were concerned, except the three extracellular protein domains (N- and C-tails, and ECL2), suggesting that structural differentiation at these domains could be related to pathogen susceptibility. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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