Transcranial Photobiomodulation Therapy in the Cognitive Rehabilitation of Patients with Cranioencephalic Trauma
| Autor: | Rodrigo Alexis Lazo Osório, Renato Amaro Zângaro, Marcelo de Lima Oliveira, Guilherme da Cruz Ribeiro Poiani, Ana Luiza Zaninnoto, Wellingson Silva Paiva, Ana Maria Costa Carneiro |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty neurological rehabilitation Time Factors Traumatic brain injury Biomedical Engineering Neuropsychological Tests Photobiomodulation—Original Research Cohort Studies Disability Evaluation Young Adult Cognition Injury Severity Score Physical medicine and rehabilitation photobiomodulation Brain Injuries Traumatic medicine Neurological rehabilitation Humans Radiology Nuclear Medicine and imaging Cognitive rehabilitation therapy Low-Level Light Therapy skin and connective tissue diseases Retrospective Studies business.industry traumatic brain injury Ultrasonography Doppler Middle Aged medicine.disease Magnetic Resonance Imaging Treatment Outcome Cerebrovascular Circulation Chronic Disease Female sense organs business Neurocognitive Brazil Follow-Up Studies |
| Zdroj: | Photobiomodulation, Photomedicine, and Laser Surgery |
| ISSN: | 2578-5478 |
| Popis: | Objective: This research evaluated the hemodynamic conditions before and after the transcranial photobiomodulation therapy (PBMT) and investigated neurocognitive changes before and after treatment. Background: Traumatic brain injury (TBI) is the major cause of morbidity and mortality among individuals 21–60 years old and causes ∼500,000 people to be hospitalized in Brazil annually. Some survivors develop an irreversible decrease in neurological function, and the mortality rate is as high as 70% in severe cases. PBMT is an alternative to treat secondary injuries due to TBI. Methods: This multidisciplinary clinical study was carried out on 10 chronic adult patients with severe TBI, who were treated with PBMT with an optical device containing 13 sets of 4 light emitting diodes, and underwent hemodynamic transcranial Doppler and neuropsychological evaluation at three different times: pre-PBMT, post-PBMT (after a week), and late-PBMT, which occurred 3 months after the last session. The patients received PBMTs three times a week, for 6 weeks. PBMTs were performed for 18 sessions for 6 weeks and 30 min per session. Results: The results found an alteration in the cerebral blood flow (CBF) as well as a consequent increase of the cerebral oxygenation that helped to improve the cerebral function. Conclusions: The PBMT contributed to increased CBF, evidenced mainly by the increased left peak systolic velocity, which consequently increased the hemodynamic response after the PBMT and impacts on the peripheral cerebral perfusion contributing to improved cerebral function. |
| Databáze: | OpenAIRE |
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