Incidence trend of type 1 diabetes mellitus in Serbia
Autor: | Antic Slobodan, Rančić Nataša, Radojkovic Danijela, Radenkovic Sasa, Kocic Radivoj, Ciric Vojislav, Pesic Milica |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Male Adolescent Endocrinology Diabetes and Metabolism Type 1 diabetes mellitus Disease lcsh:Diseases of the endocrine glands. Clinical endocrinology Young Adult Diabetes mellitus Incidence trends Trend Medicine Humans Young adult Age of Onset Child Type 1 diabetes lcsh:RC648-665 business.industry Incidence (epidemiology) Incidence Infant Newborn Type 2 Diabetes Mellitus Infant General Medicine medicine.disease Prognosis Confidence interval Diabetes Mellitus Type 1 Child Preschool Age differences Female business Serbia Demography Research Article Follow-Up Studies |
Zdroj: | BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-7 (2020) BMC Endocrine Disorders |
ISSN: | 1472-6823 |
Popis: | Background The incidence of type 1 diabetes mellitus (T1DM) increased worldwide. The objective of the paper was to compare the incidence trend of T1DM in children and adolescents aged 0–19 and in adults under 30 years of age in Serbia from 2006 to 2017. Additional aim was to compare incidence rates of T1DM and type 2 diabetes mellitus (T2DM) among adults aged 20–24 and 25–29 years of age. Methods Trends and annual percentage change (APC) of the incidence rate with corresponding 95% confidence intervals (CI) were calculated by Joinpoint Regression Analyses. Results We found a significant increase of incidence in children aged 5–9 with the APC of 5.7% (95%CI: 2.3–9.1), and in children aged 10–14 with the APC of 2.1% (95%CI: 0.6–3.6). A significant decrease of incidence was determined in adolescents aged 15–19 with the APC -4.9% (95%CI: − 8.9 to – 0.7) and in adults aged 25–29 with the APC -7.3% (95%CI: − 12.5 to − 1.8). Conclusion The increase of incidence in children aged 0–14 and its decrease after 15 years of age showed that T1DM is predominantly a metabolic disease of children in Serbia. A significant increase in incidence was recorded in two age groups, namely 5–9 and 10–14 years of age. The highest increase was in children aged 5–9 and the highest incidence rate was in children aged 10–14. An insignificant increasing of T2DM incidence was observed in young adults aged 25–29. The increase in incidence rates in children, but not in young adults, suggests that the precipitating factors of children-onset disease may differ from those of adult-onset T1DM. |
Databáze: | OpenAIRE |
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