Use of antibiotics to treat humans and animals in Uganda: a cross-sectional survey of households and farmers in rural, urban and peri-urban settings
| Autor: | Miriam Kayendeke, Laurie Denyer Willis, Sarah G. Staedke, Susan Nayiga, Clare I R Chandler, Christine Nabirye |
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| Přispěvatelé: | Nayiga, Susan [0000-0002-1895-4035], Apollo - University of Cambridge Repository |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.drug_class Farming environment Cross-sectional study 030106 microbiology Antibiotics 32 Biomedical and Clinical Sciences Convenience sample 03 medical and health sciences 0302 clinical medicine Clinical Research Environmental health medicine AcademicSubjects/MED00740 030212 general & internal medicine Antibiotic use 5 Development of treatments and therapeutic interventions 3202 Clinical Sciences business.industry Prevention 3 Good Health and Well Being Amoxicillin Oxytetracycline Hydrochloride Metronidazole AcademicSubjects/MED00290 5.1 Pharmaceuticals HIV/AIDS Original Article Infection business AcademicSubjects/MED00230 medicine.drug |
| Zdroj: | JAC-Antimicrobial Resistance |
| ISSN: | 2632-1823 |
| Popis: | Background Use of antibiotics to treat humans and animals is increasing worldwide, but evidence from low- and middle-income countries (LMICs) is limited. We conducted cross-sectional surveys in households and farms in Uganda to assess patterns of antibiotic use among humans and animals. Methods Between May and December 2018, a convenience sample of 100 households in Nagongera (rural), 174 households in Namuwongo (urban) and 115 poultry and piggery farms in Wakiso (peri-urban) were selected and enrolled. Using the ‘drug bag’ method, participants identified antibiotics they used frequently and the sources of these medicines. Prevalence outcomes were compared between different sites using prevalence ratios (PRs) and chi-squared tests. Results Nearly all respondents in Nagongera and Namuwongo reported using antibiotics to treat household members, most within the past month (74.7% Nagongera versus 68.8% Namuwongo, P = 0.33). Use of metronidazole was significantly more common in Namuwongo than in Nagongera (73.6% versus 40.0%, PR 0.54, 95% CI: 0.42–0.70, P Conclusions Antibiotics are used differently across Uganda. Further research is needed to understand why antibiotics are relied upon in different ways in different contexts. Efforts to optimize antibiotic use should be tailored to specific settings. |
| Databáze: | OpenAIRE |
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